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Modeling combinations of antiretroviral agents in vitro with integration of pharmacokinetics: guidance in regimen choice for clinical trial evaluation
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Published in: | Antimicrobial Agents and Chemotherapy 1996-05, Vol.40 (5), p.1143-1147 |
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creator | DRUSANO, G. L PRICHARD, M BILELLO, P. A BILELLO, J. A |
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Print ISSN:
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.40.5.1143</identifier><identifier>PMID: 8723455</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>AIDS/HIV ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - administration & dosage ; Antiviral Agents - pharmacokinetics ; Biological and medical sciences ; Cell Line ; Clinical Trials, Phase I as Topic ; Clinical Trials, Phase II as Topic ; Drug Administration Schedule ; Drug Therapy, Combination ; HIV Infections - drug therapy ; HIV Protease Inhibitors - pharmacology ; HIV-1 - drug effects ; human immunodeficiency virus ; Medical sciences ; Methylurea Compounds ; Methylurea Compounds - administration & dosage ; Methylurea Compounds - pharmacokinetics ; Models, Biological ; Monte Carlo Method ; Pharmacology. Drug treatments ; Pyridines ; Pyridines - administration & dosage ; Pyridines - pharmacokinetics ; Zidovudine ; Zidovudine - administration & dosage ; Zidovudine - pharmacokinetics</subject><ispartof>Antimicrobial Agents and Chemotherapy, 1996-05, Vol.40 (5), p.1143-1147</ispartof><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a502t-17d6cac8087313fa61f6d91399283babca0ad7d0d0665e9eb71813d9b25917fb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.asm.org/doi/pdf/10.1128/AAC.40.5.1143$$EPDF$$P50$$Gasm2$$H</linktopdf><linktohtml>$$Uhttps://journals.asm.org/doi/full/10.1128/AAC.40.5.1143$$EHTML$$P50$$Gasm2$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,27924,27925,52751,52752,52753,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3068993$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8723455$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DRUSANO, G. L</creatorcontrib><creatorcontrib>PRICHARD, M</creatorcontrib><creatorcontrib>BILELLO, P. A</creatorcontrib><creatorcontrib>BILELLO, J. A</creatorcontrib><title>Modeling combinations of antiretroviral agents in vitro with integration of pharmacokinetics: guidance in regimen choice for clinical trial evaluation</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Services
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</description><subject>AIDS/HIV</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Antiviral Agents - administration & dosage</subject><subject>Antiviral Agents - pharmacokinetics</subject><subject>Biological and medical sciences</subject><subject>Cell Line</subject><subject>Clinical Trials, Phase I as Topic</subject><subject>Clinical Trials, Phase II as Topic</subject><subject>Drug Administration Schedule</subject><subject>Drug Therapy, Combination</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Protease Inhibitors - pharmacology</subject><subject>HIV-1 - drug effects</subject><subject>human immunodeficiency virus</subject><subject>Medical sciences</subject><subject>Methylurea Compounds</subject><subject>Methylurea Compounds - administration & dosage</subject><subject>Methylurea Compounds - pharmacokinetics</subject><subject>Models, Biological</subject><subject>Monte Carlo Method</subject><subject>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>8723455</pmid><doi>10.1128/AAC.40.5.1143</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | AIDS/HIV Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - administration & dosage Antiviral Agents - pharmacokinetics Biological and medical sciences Cell Line Clinical Trials, Phase I as Topic Clinical Trials, Phase II as Topic Drug Administration Schedule Drug Therapy, Combination HIV Infections - drug therapy HIV Protease Inhibitors - pharmacology HIV-1 - drug effects human immunodeficiency virus Medical sciences Methylurea Compounds Methylurea Compounds - administration & dosage Methylurea Compounds - pharmacokinetics Models, Biological Monte Carlo Method Pharmacology. Drug treatments Pyridines Pyridines - administration & dosage Pyridines - pharmacokinetics Zidovudine Zidovudine - administration & dosage Zidovudine - pharmacokinetics |
title | Modeling combinations of antiretroviral agents in vitro with integration of pharmacokinetics: guidance in regimen choice for clinical trial evaluation |
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