Accumulation of 3-Ketosteroids Induced by Itraconazole in Azole-Resistant Clinical Candida albicans Isolates

• Published in: Antimicrobial Agents and Chemotherapy 1999-11, Vol.43 (11), p.2663-2670
• Main Authors: MARICHAL, P, GORRENS, J, ODDS, F, VANDEN BOSSCHE, H, LAURIJSSENS, L, VERMUYTEN, K, VAN HOVE, C, LE JEUNE, L, VERHASSELT, P, SANGLARD, D, BORGERS, M, RAMAEKERS, F. C. S
• Format: Article
• Language: English
• Subjects: Antibiotics. Antiinfectious agents. Antiparasitic agents; Antifungal Agents; Antifungal Agents - pharmacology; Azoles; Azoles - pharmacology; Biological and medical sciences; Candida albicans; Candida albicans - drug effects; Candida albicans - metabolism; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Drug Resistance, Microbial; Ergosterol - biosynthesis; Itraconazole; Itraconazole - pharmacology; Ketosteroids; Ketosteroids - metabolism; Mechanisms of Resistance; Medical sciences; Microbial Sensitivity Tests; Mixed Function Oxygenases - genetics; Mixed Function Oxygenases - metabolism; Pharmacology. Drug treatments; Polymerase Chain Reaction; Trans-Activators; Transcription Factors - genetics; Transcription Factors - metabolism; Transcriptional Regulator ERG
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.43.11.2663

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