In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens

Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. ma...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical microbiology 2010-07, Vol.48 (7), p.2546-2549
Main Authors: Tsakris, Athanassios, Voulgari, Evangelia, Poulou, Aggeliki, Kimouli, Maria, Pournaras, Spyros, Ranellou, Kyriaki, Kosmopoulou, Olga, Petropoulou, Dimitra
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833
cites cdi_FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833
container_end_page 2549
container_issue 7
container_start_page 2546
container_title Journal of clinical microbiology
container_volume 48
creator Tsakris, Athanassios
Voulgari, Evangelia
Poulou, Aggeliki
Kimouli, Maria
Pournaras, Spyros
Ranellou, Kyriaki
Kosmopoulou, Olga
Petropoulou, Dimitra
description Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla KPC-2 gene during the hospitalization.
doi_str_mv 10.1128/JCM.00264-10
format article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1128_JCM_00264_10</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1128_JCM_00264_10</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833</originalsourceid><addsrcrecordid>eNotkF9LwzAUxYMoOKdvfoB8ADPvTZomfRxF53TDgX_wrSTprUS6Vpsp-O3t1KcDh3MOhx9j5wgzRGkvb8v1DEDmmUA4YBOEwoo8h5dDNgEotEBU5pidpPQGgFmm9YTRsuPP8avn8_DxGVPcxb7jfcMd37QubWMt1lRHt6Oa-9bxu00pJF9QR9xt--6Vl23fuZYvU9-OobSvPtAwuF10fOuGQClQl07ZUePaRGf_OmVP11eP5Y1Y3S-W5XwlAqIFEZQhS1iACTJz1oMELNAbZzRQKHLvfcgtjBGvGqp1XSutjEdjUEtplZqyi7_dMPQpDdRU70Mcb3xXCNUeUTUiqn4RjY76AUKzV_0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens</title><source>PubMed Central (Open Access)</source><source>American Society for Microbiology (ASM) Journals</source><creator>Tsakris, Athanassios ; Voulgari, Evangelia ; Poulou, Aggeliki ; Kimouli, Maria ; Pournaras, Spyros ; Ranellou, Kyriaki ; Kosmopoulou, Olga ; Petropoulou, Dimitra</creator><creatorcontrib>Tsakris, Athanassios ; Voulgari, Evangelia ; Poulou, Aggeliki ; Kimouli, Maria ; Pournaras, Spyros ; Ranellou, Kyriaki ; Kosmopoulou, Olga ; Petropoulou, Dimitra</creatorcontrib><description>Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla KPC-2 gene during the hospitalization.</description><identifier>ISSN: 0095-1137</identifier><identifier>EISSN: 1098-660X</identifier><identifier>DOI: 10.1128/JCM.00264-10</identifier><language>eng</language><ispartof>Journal of clinical microbiology, 2010-07, Vol.48 (7), p.2546-2549</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833</citedby><cites>FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,3186,27922,27923</link.rule.ids></links><search><creatorcontrib>Tsakris, Athanassios</creatorcontrib><creatorcontrib>Voulgari, Evangelia</creatorcontrib><creatorcontrib>Poulou, Aggeliki</creatorcontrib><creatorcontrib>Kimouli, Maria</creatorcontrib><creatorcontrib>Pournaras, Spyros</creatorcontrib><creatorcontrib>Ranellou, Kyriaki</creatorcontrib><creatorcontrib>Kosmopoulou, Olga</creatorcontrib><creatorcontrib>Petropoulou, Dimitra</creatorcontrib><title>In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens</title><title>Journal of clinical microbiology</title><description>Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla KPC-2 gene during the hospitalization.</description><issn>0095-1137</issn><issn>1098-660X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNotkF9LwzAUxYMoOKdvfoB8ADPvTZomfRxF53TDgX_wrSTprUS6Vpsp-O3t1KcDh3MOhx9j5wgzRGkvb8v1DEDmmUA4YBOEwoo8h5dDNgEotEBU5pidpPQGgFmm9YTRsuPP8avn8_DxGVPcxb7jfcMd37QubWMt1lRHt6Oa-9bxu00pJF9QR9xt--6Vl23fuZYvU9-OobSvPtAwuF10fOuGQClQl07ZUePaRGf_OmVP11eP5Y1Y3S-W5XwlAqIFEZQhS1iACTJz1oMELNAbZzRQKHLvfcgtjBGvGqp1XSutjEdjUEtplZqyi7_dMPQpDdRU70Mcb3xXCNUeUTUiqn4RjY76AUKzV_0</recordid><startdate>201007</startdate><enddate>201007</enddate><creator>Tsakris, Athanassios</creator><creator>Voulgari, Evangelia</creator><creator>Poulou, Aggeliki</creator><creator>Kimouli, Maria</creator><creator>Pournaras, Spyros</creator><creator>Ranellou, Kyriaki</creator><creator>Kosmopoulou, Olga</creator><creator>Petropoulou, Dimitra</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201007</creationdate><title>In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens</title><author>Tsakris, Athanassios ; Voulgari, Evangelia ; Poulou, Aggeliki ; Kimouli, Maria ; Pournaras, Spyros ; Ranellou, Kyriaki ; Kosmopoulou, Olga ; Petropoulou, Dimitra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsakris, Athanassios</creatorcontrib><creatorcontrib>Voulgari, Evangelia</creatorcontrib><creatorcontrib>Poulou, Aggeliki</creatorcontrib><creatorcontrib>Kimouli, Maria</creatorcontrib><creatorcontrib>Pournaras, Spyros</creatorcontrib><creatorcontrib>Ranellou, Kyriaki</creatorcontrib><creatorcontrib>Kosmopoulou, Olga</creatorcontrib><creatorcontrib>Petropoulou, Dimitra</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of clinical microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsakris, Athanassios</au><au>Voulgari, Evangelia</au><au>Poulou, Aggeliki</au><au>Kimouli, Maria</au><au>Pournaras, Spyros</au><au>Ranellou, Kyriaki</au><au>Kosmopoulou, Olga</au><au>Petropoulou, Dimitra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens</atitle><jtitle>Journal of clinical microbiology</jtitle><date>2010-07</date><risdate>2010</risdate><volume>48</volume><issue>7</issue><spage>2546</spage><epage>2549</epage><pages>2546-2549</pages><issn>0095-1137</issn><eissn>1098-660X</eissn><abstract>Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla KPC-2 gene during the hospitalization.</abstract><doi>10.1128/JCM.00264-10</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0095-1137
ispartof Journal of clinical microbiology, 2010-07, Vol.48 (7), p.2546-2549
issn 0095-1137
1098-660X
language eng
recordid cdi_crossref_primary_10_1128_JCM_00264_10
source PubMed Central (Open Access); American Society for Microbiology (ASM) Journals
title In Vivo Acquisition of a Plasmid-Mediated bla KPC-2 Gene among Clonal Isolates of Serratia marcescens
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T12%3A03%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=In%20Vivo%20Acquisition%20of%20a%20Plasmid-Mediated%20bla%20KPC-2%20Gene%20among%20Clonal%20Isolates%20of%20Serratia%20marcescens&rft.jtitle=Journal%20of%20clinical%20microbiology&rft.au=Tsakris,%20Athanassios&rft.date=2010-07&rft.volume=48&rft.issue=7&rft.spage=2546&rft.epage=2549&rft.pages=2546-2549&rft.issn=0095-1137&rft.eissn=1098-660X&rft_id=info:doi/10.1128/JCM.00264-10&rft_dat=%3Ccrossref%3E10_1128_JCM_00264_10%3C/crossref%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c1180-c37e8e1907c24a8b020191b7a750ec96bbbc6808e1b3fed5dd3537b1771522833%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true