In Vivo IS 6110 Profile Changes in a Mycobacterium tuberculosis Strain as Determined by Tracking over 14 Years

Transposition and homologous recombination of IS 6110 appear in Mycobacterium tuberculosis along in vivo sequential infections. These events were checked in different clones of a successful strain, M. tuberculosis Zaragoza, with the focus on a variant in which integration of a copy of IS 6110 in the...

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Bibliographic Details
Published in:Journal of clinical microbiology 2015-07, Vol.53 (7), p.2359-2361
Main Authors: Millán-Lou, María Isabel, Otal, Isabel, Monforte, María Luisa, Vitoria, María Asunción, Revillo, María José, Martín, Carlos, Samper, Sofía
Format: Article
Language:English
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Summary:Transposition and homologous recombination of IS 6110 appear in Mycobacterium tuberculosis along in vivo sequential infections. These events were checked in different clones of a successful strain, M. tuberculosis Zaragoza, with the focus on a variant in which integration of a copy of IS 6110 in the origin of replication ( oriC ) region occurred.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00607-15