Mupirocin Resistance Related to Increasing Mupirocin Use in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus in a Pediatric Population

We investigated the proportion of methicillin-resistant Staphylococcus aureus (MRSA) isolates from pediatric patients demonstrating mupirocin resistance related to mupirocin use at our institution. No mupirocin resistance was found in 98% of isolates, whereas mupirocin prescriptions increased by 110...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2010-07, Vol.48 (7), p.2599-2600
Main Authors: Hogue, Jacob S, Buttke, Patricia, Braun, LoRanee E, Fairchok, Mary P
Format: Article
Language:English
Subjects:
Adolescent
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Bacteriology
Biological and medical sciences
Child
Child, Preschool
Drug Resistance, Bacterial
Female
Fundamental and applied biological sciences. Psychology
Humans
Infant
Infant, Newborn
Male
Methicillin-Resistant Staphylococcus aureus - drug effects
Microbiology
Miscellaneous
Mupirocin - pharmacology
Mupirocin - therapeutic use
Staphylococcal Infections - drug therapy
Staphylococcal Infections - microbiology
Staphylococcus aureus
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Summary:We investigated the proportion of methicillin-resistant Staphylococcus aureus (MRSA) isolates from pediatric patients demonstrating mupirocin resistance related to mupirocin use at our institution. No mupirocin resistance was found in 98% of isolates, whereas mupirocin prescriptions increased by 110%. Resistance rates remained low despite the increasing use of mupirocin.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.02118-09