Lipin 1 Represses NFATc4 Transcriptional Activity in Adipocytes To Inhibit Secretion of Inflammatory Factors

• Published in: Molecular and Cellular Biology 2010-06, Vol.30 (12), p.3126-3139
• Main Authors: Kim, Hyun Bae, Kumar, Anil, Wang, Lifu, Liu, Guang-Hui, Keller, Susanna R., Lawrence, John C., Finck, Brian N., Harris, Thurl E.
• Format: Article
• Language: English
• Subjects: 3T3-L1 Cells; Adipocytes - drug effects; Adipocytes - metabolism; Aging - metabolism; Animals; Calcium Signaling - drug effects; DNA - metabolism; Gene Expression Regulation - drug effects; Histone Deacetylases - metabolism; Hydroxamic Acids - pharmacology; Inflammation Mediators - metabolism; Mice; NFATC Transcription Factors - genetics; Nuclear Proteins - deficiency; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Obesity - genetics; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphatidate Phosphatase; PPAR alpha - metabolism; Promoter Regions, Genetic - genetics; Protein Binding - drug effects; Repressor Proteins - metabolism; RNA, Messenger - genetics; RNA, Messenger - metabolism; Trans-Activators - metabolism; Transcription Factors; Transcription, Genetic - drug effects; Tumor Necrosis Factor-alpha - genetics; Tumor Necrosis Factor-alpha - metabolism
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.01671-09

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