Characteristics of Genomic Distribution of Runs of Homozygosity in the Indigenous Population of Northern Eurasia

Populations of the indigenous ethnic groups of Northern Eurasia are of considerable interest for population genomics, both because they have been relatively poorly studied with the use of modern genomic technologies and owing to the specificity of their gene pools that developed in various genetic-d...

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Bibliographic Details
Published in:Russian journal of genetics 2019-10, Vol.55 (10), p.1294-1298
Main Authors: Kolesnikov, N. A., Kharkov, V. N., Zarubin, A. A., Stepanov, V. A.
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Biomedical and Life Sciences
Biomedicine
Human Genetics
Microbial Genetics and Genomics
Short Communications
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Summary:Populations of the indigenous ethnic groups of Northern Eurasia are of considerable interest for population genomics, both because they have been relatively poorly studied with the use of modern genomic technologies and owing to the specificity of their gene pools that developed in various genetic-demographic conditions. We used genotype data on 242 179 autosomal SNPs of 876 individuals to search for regions with runs of homozygosity of more than 1 Mb. For Siberian populations, the number of runs of homozygosity and their total length was higher than for other populations of Northern Eurasia.
ISSN:1022-7954
1608-3369
DOI:10.1134/S1022795419100077