Transcription of the hlyIIR Gene of Bacillus cereus

The transcription of the hlyIIR gene of Bacillus cereus , which is a negative transcriptional regulator of the hlyII gene of hemolysin II, the virulence factor of B. cereus , has been studied. The sequence of the promoter upstream of the hlyIIR gene was identified and the start point of transcriptio...

Full description

Saved in:
Bibliographic Details
Published in:Russian journal of genetics 2021-06, Vol.57 (6), p.662-668
Main Authors: Nagel, A. S., Andreeva-Kovalevskaya, Zh. I., Siunov, A. V., Nagornykh, M. O., Zakharova, M. V., Solonin, A. S.
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Biomedical and Life Sciences
Biomedicine
Genetics of Microorganisms
Human Genetics
Microbial Genetics and Genomics
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The transcription of the hlyIIR gene of Bacillus cereus , which is a negative transcriptional regulator of the hlyII gene of hemolysin II, the virulence factor of B. cereus , has been studied. The sequence of the promoter upstream of the hlyIIR gene was identified and the start point of transcription was determined. The effect of HlyIIR on the transcription of its own promoter was analyzed in vitro and in vivo. The constitutive synthesis of the final product was revealed in B. cereus . The results indicate the absence of autoregulation of the hlyIIR gene and the absence of involvement of the hemolysin II gene promoter in regulation of the hlyIIR gene expression.
ISSN:1022-7954
1608-3369
DOI:10.1134/S1022795421060077