Expression Profile and Relationships between microRNAs as Biomarkers in COPD Patients

Chronic obstructive pulmonary disease is a chronic inflammatory lung disease that causes airflow obstruction in the lungs. In fact, it is a lung disease that can cause involvement of respiratory tracts, lung tissue or blood vessels. There is still no accurate diagnostic tool for COPD. Among various...

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Bibliographic Details
Published in:Russian journal of genetics 2024-04, Vol.60 (4), p.433-449
Main Authors: Moattar-Husseini, N., Bahrami, N., Hosseini, F., Jamaati, H., Kazempour-Dizaji, M., Shafaghi, Sh, Noorali, S., Mohamadnia, A.
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Biomedical and Life Sciences
Biomedicine
Human Genetics
Microbial Genetics and Genomics
Reviews and Theoretical Articles
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Summary:Chronic obstructive pulmonary disease is a chronic inflammatory lung disease that causes airflow obstruction in the lungs. In fact, it is a lung disease that can cause involvement of respiratory tracts, lung tissue or blood vessels. There is still no accurate diagnostic tool for COPD. Among various biomarkers, the current review focuses on different types of miRNAs in COPD which have been studied. Many target cells and molecules, microRNAs are involved in the pathogenesis of COPD. MicroRNAs are a group of protected short single-stranded RNAs between 19 and 23 nucleotides and non-coding, which act as post-transcriptional regulators in animals, plants and viruses. In this article, the aim is to collect and categorize the studies conducted in the field of microRNA as biomarkers in COPD patients.
ISSN:1022-7954
1608-3369
DOI:10.1134/S1022795424040082