Human chemical status and endothelial function

In order to study the microelement composition of human blood and endothelial function, we examined a sampling of 49 people with an average age of 59.4 ± 1.07 years. To evaluate microcirculation, we studied three vasoactive substances: adrenaline, acetylcholine, and histamine. Using X-ray fluorescen...

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Published in:Surface investigation, x-ray, synchrotron and neutron techniques x-ray, synchrotron and neutron techniques, 2011-12, Vol.5 (6), p.1098-1101
Main Authors: Zhuravskaya, E. Ya, Nikolaev, K. Yu, Gyrgol’kau, L. A., Kutsenogii, K. P., Chankina, O. V., Savchenko, T. I.
Format: Article
Language:English
Subjects:
Chemistry and Materials Science
Materials Science
Novosibirsk
Proceedings of XVIII International Conference on the Application of Synchrotron Radiation SR-2010 (Budker INP SB RAS
Russia
Surfaces and Interfaces
Thin Films
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Summary:In order to study the microelement composition of human blood and endothelial function, we examined a sampling of 49 people with an average age of 59.4 ± 1.07 years. To evaluate microcirculation, we studied three vasoactive substances: adrenaline, acetylcholine, and histamine. Using X-ray fluorescence analysis with synchrotron radiation, we studied the contents of a wide array of chemical elements contained in blood (Ca, Fe, Cu, Zn, Se, Br, Rb, Sr, Pb, and K). We analyzed certain risk factors of cardiovascular diseases. We’ve discovered and interrelation of certain chemical elements and vascular reactivity to adrenaline and acetylcholine. Thus, the complex of microelement can be a potential factor related to endothelial dysfunction in cardiovascular diseases.
ISSN:1027-4510
1819-7094
DOI:10.1134/S102745101111022X