Procedure for the analysis of sedative drugs with the use of an array of piezoelectric sensors (Exemplified in the determination of the drug Corvalol)

A procedure was developed for the headspace analysis of sedative drugs with the use of a quartz piezoelectric microbalance array. The effects of the nature of film coatings in piezoelectric cell electrodes on the working weight range and the sorption properties of sorbent films were found. An array...

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Bibliographic Details
Published in:Journal of analytical chemistry (New York, N.Y.) N.Y.), 2008-03, Vol.63 (3), p.285-291
Main Authors: Kuchmenko, T. A., Kozhukhova, A. V., Orobinskii, Yu. I.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Chemistry
Chemistry and Materials Science
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Summary:A procedure was developed for the headspace analysis of sedative drugs with the use of a quartz piezoelectric microbalance array. The effects of the nature of film coatings in piezoelectric cell electrodes on the working weight range and the sorption properties of sorbent films were found. An array of six piezoelectric sensors with different response functions in the vapors of the drug Corvalol and its highly volatile constituents was proposed. The procedure is suitable for the quality assessment of other pharmaceuticals based on ethyl alcohol and natural peppermint oil.
ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934808030179