Melatonin effect on the regeneration of the flatworm Girardia tigrina

The melatonin effect on the anterior and posterior ends of a free-living flatworm Girardia tigrina was studied, as well as the variability of the mitotic activity of the stem cells (neoblasts) in the anterior and posterior postblasteme. This hormone may inhibit the regeneration of the anterior end o...

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Bibliographic Details
Published in:Russian journal of developmental biology 2009-11, Vol.40 (6), p.382-385
Main Authors: Yermakova, O. N, Yermakov, A. M, Tiras, Kh. P, Lednev, V. V
Format: Article
Language:English
Subjects:
Animal Anatomy
Biomedical and Life Sciences
Developmental Biology
Histology
Life Sciences
melatonin
Morphology
neoblasts
Platyhelminthes
regeneration
Short Communications
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Summary:The melatonin effect on the anterior and posterior ends of a free-living flatworm Girardia tigrina was studied, as well as the variability of the mitotic activity of the stem cells (neoblasts) in the anterior and posterior postblasteme. This hormone may inhibit the regeneration of the anterior end of the animal in the physiologic-friendly concentrations of 10⁻¹⁰-10⁻⁵ M by suppressing the mitotic activity of the neoblasts. This hormone does not affect the posterior end's regeneration; thus, its regeneration effect is significantly elective.
ISSN:1062-3604
1608-3326
DOI:10.1134/S1062360409060083