total large-scale synthesis of argiopine

The total large-scale synthesis of a natural toxin argiopine, a polymethylenepolyamine derivative, was developed. It consisted of 26 stages and included three key block schemes. Most of the stages proceeded quantitatively, which excluded the necessity of using the chromatographic separation of inter...

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Bibliographic Details
Published in:Russian journal of bioorganic chemistry 2009-11, Vol.35 (6), p.752-758
Main Authors: Formanovsky, A. A, Popova, I. S, Mikhura, I. V
Format: Article
Language:English
Subjects:
argiopine
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Experimental Article
Life Sciences
Organic Chemistry
polymethylenepolyamines
synthesis
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Summary:The total large-scale synthesis of a natural toxin argiopine, a polymethylenepolyamine derivative, was developed. It consisted of 26 stages and included three key block schemes. Most of the stages proceeded quantitatively, which excluded the necessity of using the chromatographic separation of intermediates.
ISSN:1068-1620
1608-330X
DOI:10.1134/S1068162009060120