The synthesis and membrane protective properties of sulfanyl imines derived from neomenthane and isobornane thiols

Neomenthane and isobornane thiol-derived sulfanyl imines were prepared in yields of up to 85%. On the basis of the capacity of the sulfanyl imines obtained to inhibit the H 2 H 2 - and AAPH-induced erythrocyte hemolysis and impede the accumulation of secondary products of lipid peroxidation and hemo...

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Bibliographic Details
Published in:Russian journal of bioorganic chemistry 2015, Vol.41 (1), p.77-82
Main Authors: Izmest’ev, E. S., Sudarikov, D. V., Shevchenko, O. G., Rubtsova, S. A., Kutchin, A. V.
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Life Sciences
Organic Chemistry
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Summary:Neomenthane and isobornane thiol-derived sulfanyl imines were prepared in yields of up to 85%. On the basis of the capacity of the sulfanyl imines obtained to inhibit the H 2 H 2 - and AAPH-induced erythrocyte hemolysis and impede the accumulation of secondary products of lipid peroxidation and hemoglobin oxidation, they were shown to display membrane protective and antioxidant properties.
ISSN:1068-1620
1608-330X
DOI:10.1134/S1068162014050070