Condensation of thiourea with uracyl derivatives containing ketone and ketoester fragments, alkylation and macrocyclization of the condensation products

By condensation of thiourea with 6-methyluracyl derivatives containing ketone and ketoester fragmenst in the alkyl chains attached to the nitrogen atoms of the pyrimidine ring the products containing 6-methyl- or 3,6-dimethyluracyl fragment and one or two 6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyri...

Full description

Saved in:
Bibliographic Details
Published in:Russian journal of general chemistry 2010-07, Vol.80 (7), p.1364-1368
Main Authors: Krylova, E. S., Semenov, V. E., Akamsin, V. D., Reznik, V. S.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:By condensation of thiourea with 6-methyluracyl derivatives containing ketone and ketoester fragmenst in the alkyl chains attached to the nitrogen atoms of the pyrimidine ring the products containing 6-methyl- or 3,6-dimethyluracyl fragment and one or two 6-methyl-4-oxo-2-thio-1,2,3,4-tetrahydropyrimidin-5-yl fragments were synthesized. These compounds can be alkylated with alkyl bromides.
ISSN:1070-3632
1608-3350
DOI:10.1134/S107036321007025X