Cycloalkaneindoles with 2-trifluoromethylimidazo[1,2-a]pyridin-6-yl fragment

Modification of biologically active cycloalkaneindoles by incorporation of a 2-trifluoromethylimidazo[1,2- a ]pyridin-6-yl fragment has been proposed and performed via the interaction with 3-fluoro-2-trifluoromethylimidazo[1,2- a ]pyridines in the presence of potassium hydroxide. The action of the p...

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Bibliographic Details
Published in:Russian journal of general chemistry 2015-06, Vol.85 (6), p.1452-1455
Main Authors: Sokolov, V. B., Aksinenko, A. Yu, Epishina, T. A., Goreva, T. V., Gabrel’yan, A. V., Dranii, O. A., Grigor’ev, V. V., Bachurin, S. O.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
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Summary:Modification of biologically active cycloalkaneindoles by incorporation of a 2-trifluoromethylimidazo[1,2- a ]pyridin-6-yl fragment has been proposed and performed via the interaction with 3-fluoro-2-trifluoromethylimidazo[1,2- a ]pyridines in the presence of potassium hydroxide. The action of the prepared compounds on neuronal NMDA receptors has been studied by means of radioligand binding.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363215060158