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Synthesis of 1,2,4-triazole-3-thiols and their S-substituted derivatives
New 1,2,4-triazole-3-thiols were synthesized by reactions of the corresponding carboxylic acid hydrazides with isothiocyanates and subsequent cyclization of intermediate 1,4-substituted thiosemicarbazides. Alkylation of 1,2,4-triazole-3-thiols with benzyl chlorides and bromacetophenones gave only S-...
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Published in: | Russian journal of organic chemistry 2010-04, Vol.46 (4), p.551-555 |
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container_issue | 4 |
container_start_page | 551 |
container_title | Russian journal of organic chemistry |
container_volume | 46 |
creator | Kochikyan, T. V Samvelyan, M. A Arutyunyan, V. S Avetisyan, A. A Tamazyan, R. A Aivazyan, A. G |
description | New 1,2,4-triazole-3-thiols were synthesized by reactions of the corresponding carboxylic acid hydrazides with isothiocyanates and subsequent cyclization of intermediate 1,4-substituted thiosemicarbazides. Alkylation of 1,2,4-triazole-3-thiols with benzyl chlorides and bromacetophenones gave only S-substituted derivatives. |
doi_str_mv | 10.1134/S1070428010040184 |
format | article |
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subjects | Chemistry Chemistry and Materials Science Organic Chemistry |
title | Synthesis of 1,2,4-triazole-3-thiols and their S-substituted derivatives |
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