Phosphonitrilic Chloride—The Dehydration of Amides to Nitriles

Phosphonitrilic chloride is found to dehydrate amides to nitriles rapidly and in high yields. A mechanism for the dehydration is proposed.

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Bibliographic Details
Published in:Canadian journal of chemistry 1972-12, Vol.50 (23), p.3857-3860
Main Authors: Graham, John C., Marr, David H.
Format: Article
Language:English
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Description
Summary:Phosphonitrilic chloride is found to dehydrate amides to nitriles rapidly and in high yields. A mechanism for the dehydration is proposed.
ISSN:0008-4042
1480-3291
DOI:10.1139/v72-607