Synthèses des alkyl-1 cyclanols fonctionnalisés aux positions α, β et γ de la chaîne hydrocarbonée

We have developed a general and versatile synthesis of N,N-dialkylaminoalkyl-, 1-chloroalkyl-, 1-phenoxyalkyl-, 1-thiophenoxyalkyl-, 1-diethyoxyalkyl-, and 1-(1,3-dithiolane)alkylcyclanols in good yields by the reaction of α,ω-bis(bromomagnesio)alkanes with the corresponding functionalized carboxyli...

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Bibliographic Details
Published in:Canadian journal of chemistry 1988-01, Vol.66 (1), p.168-173
Main Authors: Canonne, P., Belley, M., Fytas, G., Plamondon, J.
Format: Article
Language:English
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Summary:We have developed a general and versatile synthesis of N,N-dialkylaminoalkyl-, 1-chloroalkyl-, 1-phenoxyalkyl-, 1-thiophenoxyalkyl-, 1-diethyoxyalkyl-, and 1-(1,3-dithiolane)alkylcyclanols in good yields by the reaction of α,ω-bis(bromomagnesio)alkanes with the corresponding functionalized carboxylic acid esters.
ISSN:0008-4042
1480-3291
DOI:10.1139/v88-026