Anwuweizonic acid and manwuweizic acid, the putative anticancer active principle of Schisandra propinqua

The structures of two new triterpenoid acids, anwuweizonic acid ( 1 ) and manwuweizic acid ( 2 ), from Schisandra propinqua are elucidated by spectroscopic evidence and chemical correlation. Compound 2 shows significant inhibitory activity against Lewis lung cancer, brain tumor-22, and solid hepatom...

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Bibliographic Details
Published in:Canadian journal of chemistry 1988-03, Vol.66 (3), p.414-415
Main Authors: Liu, Jia-Sen, Huang, Mei-Fen, Tao, Yong
Format: Article
Language:English
Subjects:
Biological and medical sciences
General pharmacology
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
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Summary:The structures of two new triterpenoid acids, anwuweizonic acid ( 1 ) and manwuweizic acid ( 2 ), from Schisandra propinqua are elucidated by spectroscopic evidence and chemical correlation. Compound 2 shows significant inhibitory activity against Lewis lung cancer, brain tumor-22, and solid hepatoma in mice, and exhibits no cytotoxic action in vitro.
ISSN:0008-4042
1480-3291
DOI:10.1139/v88-072