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Giant Vesicle Fusion on Microelectrodes Fabricated by Femtosecond Laser Ablation Followed by Synchrotron Radiation Etching
We have developed a new technique for fabricating a hole (well) with a diameter of about 1 µm for a microelectrode on the surface of SiO 2 (600 nm)/CoSi 2 (10 nm)/Si substrate. This process enabled the fabrication of electrode holes while maintaining the original nanolevel flatness ( R a ∼0.8 nm) of...
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Published in: | Japanese Journal of Applied Physics 2005-01, Vol.44 (9L), p.L1207 |
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Main Authors: | , , , , , , , , , , , |
Format: | Article |
Language: | English |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | We have developed a new technique for fabricating a hole (well) with a diameter of about 1 µm for a microelectrode on the surface of SiO
2
(600 nm)/CoSi
2
(10 nm)/Si substrate. This process enabled the fabrication of electrode holes while maintaining the original nanolevel flatness (
R
a
∼0.8 nm) of the SiO
2
surface. A lipid bilayer was formed by giant vesicle fusion on these microelectrodes. Fluorescence microscope,
in situ
atomic force microscope and electrical characteristics measurements showed that a single lipid bilayer of sufficiently high resistance (gigaohm seal) was successfully fabricated. |
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ISSN: | 0021-4922 1347-4065 |
DOI: | 10.1143/JJAP.44.L1207 |