Visual Function, Organization, and Development of the Mouse Superior Colliculus

The superior colliculus (SC) is the most prominent visual center in mice. Studies over the past decade have greatly advanced our understanding of the function, organization, and development of the mouse SC, which has rapidly become a popular model in vision research. These studies have described the...

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Bibliographic Details
Published in:Annual review of vision science 2018-09, Vol.4 (1), p.239-262
Main Authors: Cang, Jianhua, Savier, Elise, Barchini, Jad, Liu, Xiaorong
Format: Article
Language:English
Subjects:
cell type
direction selectivity
map alignment
orientation selectivity
receptive fields
retinotopic maps
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Summary:The superior colliculus (SC) is the most prominent visual center in mice. Studies over the past decade have greatly advanced our understanding of the function, organization, and development of the mouse SC, which has rapidly become a popular model in vision research. These studies have described the diverse and cell-type-specific visual response properties in the mouse SC, revealed their laminar and topographic organizations, and linked the mouse SC and downstream pathways with visually guided behaviors. Here, we summarize these findings, compare them with the rich literature of SC studies in other species, and highlight important gaps and exciting future directions. Given its clear importance in mouse vision and the available modern neuroscience tools, the mouse SC holds great promise for understanding the cellular, circuit, and developmental mechanisms that underlie visual processing, sensorimotor transformation, and, ultimately, behavior.
ISSN:2374-4642
2374-4650
DOI:10.1146/annurev-vision-091517-034142