The Bathtub Method for Detecting Small Quantities of Specific Pathogens

This paper presents a rapid method for detecting small quantities of specific bacteria. The method combines phage-coated magnetoelastic (ME) biosensors, microfabricated arrayed bathtubs for cell culture, a surface-scanning detector, and a motorized translation system, enabling real-time monitoring o...

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Bibliographic Details
Published in:ECS transactions 2016-01, Vol.75 (16), p.183-192
Main Authors: Horikawa, Shin, Du, Songtao, Liu, Yuzhe, Chen, I-Hsuan, Chai, Yating, Wikle, Howard Clyde, Chin, Bryan A
Format: Article
Language:English
Online Access:Get full text
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Summary:This paper presents a rapid method for detecting small quantities of specific bacteria. The method combines phage-coated magnetoelastic (ME) biosensors, microfabricated arrayed bathtubs for cell culture, a surface-scanning detector, and a motorized translation system, enabling real-time monitoring of the growth of specific bacteria in a nutrient broth. Rapid detectionof a few bacterial cells is possible, depending on the sensor size and efficiency of bacterial growth.
ISSN:1938-5862
1938-6737
DOI:10.1149/07516.0183ecst