Exploiting Nanobiophotonics for Enhanced Optical Biosensor Platforms

In this presentation we describe strategies that will yield substantial enhancements in the analytical performance of fluorescence-based biochip platforms, especially for biomedical diagnostic applications. In particular, the focus is on optimisation of the signal-to-noise ratio (SNR) with a view to...

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Main Authors: MacCraith, Brian D., McDonagh, Colette, Stranik, Ondra, Kurzbuch, D., Nooney, R., Le Guevel, X.
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creator MacCraith, Brian D.
McDonagh, Colette
Stranik, Ondra
Kurzbuch, D.
Nooney, R.
Le Guevel, X.
description In this presentation we describe strategies that will yield substantial enhancements in the analytical performance of fluorescence-based biochip platforms, especially for biomedical diagnostic applications. In particular, the focus is on optimisation of the signal-to-noise ratio (SNR) with a view to lowering the limit of detection (LOD). These strategies include exploitation of plasmonic effects and high-brightness doped-silica nanoparticles. The advantages offered by capturing supercritical angle fluorescence (SAF) are also covered.
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title Exploiting Nanobiophotonics for Enhanced Optical Biosensor Platforms
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