Randomized trial of progressive resistance training to counteract the myopathy of chronic heart failure

1  Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston 02111; 2  Brockton West Roxbury Veterans Affairs Medical Center, Division on Aging, Harvard Medical School, Boston 0213...

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Bibliographic Details
Published in:Journal of applied physiology (1985) 2001-06, Vol.90 (6), p.2341-2350
Main Authors: Pu, Charles T, Johnson, Meredith T, Forman, Daniel E, Hausdorff, Jeffrey M, Roubenoff, Ronenn, Foldvari, Mona, Fielding, Roger A, Singh, Maria A. Fiatarone
Format: Article
Language:English
Subjects:
Adaptation, Physiological
Aged
Aging
Biological and medical sciences
Body Weight - physiology
Cardiology. Vascular system
Chronic Disease
Exercise
Exercise Therapy
Female
Heart
Heart failure
Heart Failure - pathology
Heart Failure - therapy
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Humans
Medical sciences
Muscle, Skeletal - pathology
Muscular system
Older people
Oxygen Consumption - physiology
Patient Compliance
Safety
Weight Lifting - physiology
Women
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Summary:1  Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston 02111; 2  Brockton West Roxbury Veterans Affairs Medical Center, Division on Aging, Harvard Medical School, Boston 02132; 3  Hebrew Rehabilitation Center for Aged, Division on Aging, Harvard Medical School, Boston 02131; 6  Department of Health Sciences, Sargeant College of Health Rehabilitation Sciences, and 4  Department of Cardiology, Boston University, and 5  Gerontology Division, Beth Israel Deaconess Hospital, Boston, Massachusetts 02215; and 7  School of Exercise and Sport Science, University of Sydney, Sydney, Australia 2141 Chronic heart failure (CHF) is characterized by a skeletal muscle myopathy not optimally addressed by current treatment paradigms or aerobic exercise. Sixteen older women with CHF were compared with 80 age-matched peers without CHF and randomized to progressive resistance training or control stretching exercises for 10 wk. Women with CHF had significantly lower muscle strength ( P  
ISSN:8750-7587
1522-1601
DOI:10.1152/jappl.2001.90.6.2341