Evaluation of In Vitro Anti‐inflammatory Activity of Azomethines of Aryl Oxazoles

Ability to inhibit erythrocyte hemolysis is often used as a characteristic of the membrane stabilising action of chemical compounds. Azomethines of aryl oxazoles were evaluated for anti‐inflammatory by in vitro hemolytic membrane stabilising study. The effect of inflammation condition was studied on...

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Bibliographic Details
Published in:E-journal of chemistry 2011, Vol.8 (S1), p.S392-S394
Main Authors: Niraimathi, V., Suresh, A. Jerad, Latha, T.
Format: Article
Language:English
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Summary:Ability to inhibit erythrocyte hemolysis is often used as a characteristic of the membrane stabilising action of chemical compounds. Azomethines of aryl oxazoles were evaluated for anti‐inflammatory by in vitro hemolytic membrane stabilising study. The effect of inflammation condition was studied on erythrocyte exposed to hypotonic solution. In this in vitro method the membrane stabilising action leads to anti‐inflammatory activity and was compared with that produced by diclofenac sodium as the reference standard. Results of the evaluation indicate that the synthesised compounds found to exhibit membrane stabilising activity.
ISSN:2090-9063
0973-4945
2090-9071
2090-9810
DOI:10.1155/2011/561759