Phase Transfer Catalysis Assisted Thorpe Reaction for the Synthesis of 3‐Aminothiophene‐2‐carboxylates

Thorpe cyclization constructing synthetically important methyl or ethyl 3‐amino‐4‐arylthiophene‐2‐carboxylates has been studied using eco friendly phase transfer catalysis technique. 3‐Amino‐4‐arylthiophene‐2‐carboxylates have been synthesized from 3‐hydroxy‐2‐arylacrylonitriles and thioglycolates u...

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Bibliographic Details
Published in:E-journal of chemistry 2011-01, Vol.8 (1), p.368-372
Main Author: Shah, R. D.
Format: Article
Language:English
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Summary:Thorpe cyclization constructing synthetically important methyl or ethyl 3‐amino‐4‐arylthiophene‐2‐carboxylates has been studied using eco friendly phase transfer catalysis technique. 3‐Amino‐4‐arylthiophene‐2‐carboxylates have been synthesized from 3‐hydroxy‐2‐arylacrylonitriles and thioglycolates under different solid‐liquid phase‐transfer conditions.
ISSN:2090-9063
0973-4945
2090-9071
2090-9810
DOI:10.1155/2011/650501