Abstract A105: Pharmacological inhibition of nicotinamide adenine dinucleotide (NAD+) production enzyme nicotinamide phosphoribosyltransferase (NAMPT) impairs cellular survival, energy metabolism, and tumor growth in neuroblastoma (NB) models

Background: Neuroblastoma is the most common extracranial solid tumor in children. High-risk patients have a poor prognosis with an overall survival rate of

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Bibliographic Details
Published in:Molecular cancer therapeutics 2023-12, Vol.22 (12_Supplement), p.A105-A105
Main Authors: Varriano, Sophia, Lee, Unsun, Collins, Victor, Nguyen, Rosa, Issaq, Sameer, Sun, Ming, Nelson, Ariana, Yeung, Choh, Thomas, Craig, Mendoza, Arnulfo, Thiele, Carol, Heske, Christine
Format: Article
Language:English
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Summary:Background: Neuroblastoma is the most common extracranial solid tumor in children. High-risk patients have a poor prognosis with an overall survival rate of
ISSN:1538-8514
1538-8514
DOI:10.1158/1535-7163.TARG-23-A105