Studies of the C3 Polymorphism

The relationship between C3 phenotypes and anti bodies against blood group antigens A and B were studied in 251 sera from newly delivered mothers and in 289 blood donor sera. Among the mothers an association was found between high titres of anti-A or anti-B and the C3 S gene. This difference was mos...

Full description

Saved in:
Bibliographic Details
Published in:Human heredity 2008-08, Vol.23 (3), p.214-219
Main Authors: Brönnestam, Rolf, Cedergren, Bertil
Format: Article
Language:English
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The relationship between C3 phenotypes and anti bodies against blood group antigens A and B were studied in 251 sera from newly delivered mothers and in 289 blood donor sera. Among the mothers an association was found between high titres of anti-A or anti-B and the C3 S gene. This difference was most pronounced in cases of ABO incompatibility between mother and infant thus suggesting an association between C3 types and immune antibodies. Among the blood donors no association was found between C3 type and isoagglutinin titre.
ISSN:0001-5652
1423-0062
DOI:10.1159/000152576