Transferrin C2 and Radiation-Induced Chromosomal Damage

Radiation-induced chromosomal damage (after exposure to 1 Gy) in lymphocytes was studied in relation to transferrin C subtype (C1 vs. C2). In 72-hour lymphocyte cultures a significantly increased frequency of cells with radiation induced aberrations was observed in individuals with the transferrin t...

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Bibliographic Details
Published in:Human heredity 1988-01, Vol.38 (1), p.56-58
Main Authors: Beckman, L., Nordenson, I.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biological effects of radiation
Chromosomes - radiation effects
Damage
DNA Damage
Eczema - genetics
Fundamental and applied biological sciences. Psychology
Humans
In Vitro Techniques
Ionizing radiations
Lymphocytes - radiation effects
Radiation, Ionizing
Short Communication
Short Communications
Smoking
Tissues, organs and organisms biophysics
Transferrin - genetics
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Summary:Radiation-induced chromosomal damage (after exposure to 1 Gy) in lymphocytes was studied in relation to transferrin C subtype (C1 vs. C2). In 72-hour lymphocyte cultures a significantly increased frequency of cells with radiation induced aberrations was observed in individuals with the transferrin type C2. Thus the results lend some support to the hypothesis that transferrin C2 may act as an enhancer of chromosomal damage.
ISSN:0001-5652
1423-0062
DOI:10.1159/000153756