Serum Homocysteine: Relationship with Circulating Levels of Cortisol and Ascorbate

Background/Aim: High serum levels of homocysteine and cortisol are independent risk factors for several pathologies and their levels can be regulated by some vitamins. Since the relationship between serum concentrations of homocysteine, cortisol and ascorbate has not been assessed in healthy individ...

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Bibliographic Details
Published in:Annals of nutrition and metabolism 2008-01, Vol.53 (1), p.67-74
Main Authors: Cascalheira, José F., Parreira, Mónica C., Viegas, Andreza N., Faria, Maria C., Domingues, Fernanda C.
Format: Article
Language:English
Subjects:
Aging - blood
Amino acids
ascorbic acid
Ascorbic Acid - blood
blood serum
Blood tests
Cardiovascular Diseases - blood
Cardiovascular Diseases - epidemiology
chronic diseases
Correlation analysis
cortisol
Female
Folic Acid - blood
Health Status
homocysteine
Homocysteine - blood
Humans
Hydrocortisone - blood
Linear Models
Male
Middle Aged
Nutrients
Nutritional Status
Original Paper
Regression analysis
Risk Factors
Steroids
Vitamins
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Summary:Background/Aim: High serum levels of homocysteine and cortisol are independent risk factors for several pathologies and their levels can be regulated by some vitamins. Since the relationship between serum concentrations of homocysteine, cortisol and ascorbate has not been assessed in healthy individuals to date, it was the topic of the present work. Methods: The study group was composed of 20 men and 40 women aged >50 years. Blood samples were collected and serum concentrations of the analytes were quantified. Results: Serum homocysteine levels correlate positively with cortisol (r = 0.36, p
ISSN:0250-6807
1421-9697
DOI:10.1159/000158636