Severe Dermatologic Reactions with Bendamustine: A Case Series

Cutaneous drug reactions make up the largest proportion of adverse events in the medical field. Causality, in particular, is difficult to determine, and therefore, preventing recurrent reactions can be challenging. Bendamustine was initially thought to be a well-tolerated chemotherapy agent with few...

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Bibliographic Details
Published in:Case reports in oncology 2014-07, Vol.7 (2), p.465-470
Main Authors: Carilli, Allison, Favis, Gregory, Sundharkrishnan, Lohini, Hajdenberg, Julio
Format: Article
Language:English
Subjects:
Adverse events
Bendamustine
Chemotherapy
Dermatologic reaction
Lymphoma
Published: July 2014
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Summary:Cutaneous drug reactions make up the largest proportion of adverse events in the medical field. Causality, in particular, is difficult to determine, and therefore, preventing recurrent reactions can be challenging. Bendamustine was initially thought to be a well-tolerated chemotherapy agent with few side effects aside from bone marrow suppression. However, the incidence of cutaneous reactions reported is rising. We describe three such reactions in relation to bendamustine administration in hopes of adding to the awareness of such side effects.
ISSN:1662-6575
1662-6575
DOI:10.1159/000365324