A Squamous Cell Carcinoma and a Malignant Fibrous Histiocytoma Developing in a Patient with a Mature Cystic Teratoma

We present a very rare case of malignant transformation of a benign mature cystic teratoma. The pathology report revealed malignant transformation of both the epithelial and sarcomatous elements of a benign dermoid cyst. To the best of our knowledge, this appears to be the third case of a malignant...

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Bibliographic Details
Published in:Case reports in oncology 2017-01, Vol.10 (1), p.98-105
Main Authors: Tahaoglu, Ali Emre, Ege, Serhat, Bakir, Mehmet Sait, Saruhan, Gülbin, Aksin, Serif, Gul, Talip
Format: Article
Language:English
Subjects:
Abdomen
Bone cancer
Case Report
Case reports
Cystic teratoma
Cysts
Fibrous histiocytoma
Gynecology
Laparoscopy
Melanoma
Metastasis
Obstetrics
Pathology
Skin cancer
Squamous cell carcinoma
Tumors
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Summary:We present a very rare case of malignant transformation of a benign mature cystic teratoma. The pathology report revealed malignant transformation of both the epithelial and sarcomatous elements of a benign dermoid cyst. To the best of our knowledge, this appears to be the third case of a malignant fibrous histiocytoma and a squamous cell carcinoma developing from a mature cystic teratoma. Malignant transformation of a dermoid cyst is usually diagnosed postmenopausally, but our patient was premenopausal. The etiology and prognosis of malignant transformation of this benign condition remain unknown.
ISSN:1662-6575
1662-6575
DOI:10.1159/000455912