Chronic Orbital Inflammation Associated to Hydroxyapatite Implants in Anophthalmic Sockets

Purpose: We report 6 patients who received a hydroxyapatite (HA) orbital implant in the socket and developed chronic orbital inflammation unresponsive to conventional medical therapy. Case Reports: We assisted 6 cases (4 males, 2 females) who received an HA orbital implant in the socket between 2015...

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Bibliographic Details
Published in:Case reports in ophthalmology 2017-12, Vol.8 (3), p.574-580
Main Authors: Galindo-Ferreiro, Alicia, Elkhamary, Sahar M., Maktabi, Azza, Galvez-Ruiz, Alberto, Schellini, Silvana Artioli
Format: Article
Language:English
Subjects:
Anophthalmic cavity
Antibiotics
Case Report
Case reports
Chronic inflammatory reaction
Gangrene
Hospitals
Hydroxyapatite
Infections
Inflammation
Integrated implant
Medical imaging
Ophthalmology
Pain
Polyethylene
Prostheses
Transplants & implants
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Summary:Purpose: We report 6 patients who received a hydroxyapatite (HA) orbital implant in the socket and developed chronic orbital inflammation unresponsive to conventional medical therapy. Case Reports: We assisted 6 cases (4 males, 2 females) who received an HA orbital implant in the socket between 2015 and 2016 at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia, and developed chronic orbital inflammation with chronic discharge, redness, and pain (onset from weeks to over 2 decades after surgery). Computed tomography evaluation indicated inflammation in the orbital tissues, and histological examination showed a foreign body granulomatous reaction mainly localized around and blanching the HA implant. The condition was unresponsive to usual medical treatment and was resolved immediately after implant removal. Conclusions: Chronic inflammation can occur decades after placement of an HA implant in the orbit and can be successfully treated with implant removal.
ISSN:1663-2699
1663-2699
DOI:10.1159/000485498