Extension of the Storage Period of Platelet Concentrates in Germany to 5 Days by Bacterial Testing: Is it Worth the Effort?

The shelf life of platelet concentrates (PCs) was limited in Germany to 4 days after the day of production because platelet-related septic complications had been observed, mainly with PCs at the end of their shelf life. The reduction in PC shelf life gives rise to several problems, including an incr...

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Bibliographic Details
Published in:Transfusion medicine and hemotherapy 2019-04, Vol.46 (2), p.111-113
Main Authors: Vollmer, Tanja, Hinse, Dennis, Diekmann, Jürgen, Knabbe, Cornelius, Dreier, Jens
Format: Article
Language:English
Subjects:
Brief Report
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Summary:The shelf life of platelet concentrates (PCs) was limited in Germany to 4 days after the day of production because platelet-related septic complications had been observed, mainly with PCs at the end of their shelf life. The reduction in PC shelf life gives rise to several problems, including an increased number of discarded products, accompanied by potential challenges of how to ensure an adequate supply of platelet products. The aim of this study was to show routine experience over the last 7 years using the Bactiflow (BF) assay to screen for bacterial contamination late in PC storage, followed by extension of PC shelf life.
ISSN:1660-3796
1660-3818
DOI:10.1159/000499543