An Unusual Presentation of Cytomegalovirus Infection: Generalized Edema

Objective: Cytomegalovirus (CMV) infection may rarely lead to protein-losing gastropathy that presents with nausea, vomiting, abdominal pain, and edema in immunocompetent children, but extremely rarely with only generalized edema. Clinical Presentation and Intervention: A previously healthy 5-year-o...

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Bibliographic Details
Published in:Medical principles and practice 2020-01, Vol.29 (1), p.94-96
Main Authors: Tuna Kirsaclioglu, Ceyda, Hizal, Gulin, Karakus, Esra, Sayli, Tulin Revide
Format: Article
Language:English
Subjects:
Abdomen
Ascites
Blood
Case Report
Case reports
Child
Children & youth
Childrens health
Cytomegalovirus
Cytomegalovirus - isolation & purification
Cytomegalovirus Infections - complications
Cytomegalovirus Infections - diagnosis
Deoxyribonucleic acid
DNA
Edema
Edema - complications
Growth factors
Hematology
Hospitals
Humans
Hyperplasia
Immunocompetence
Infections
Laboratories
Male
Oncology
Pediatrics
Proteins
Ulcers
Vomiting
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Summary:Objective: Cytomegalovirus (CMV) infection may rarely lead to protein-losing gastropathy that presents with nausea, vomiting, abdominal pain, and edema in immunocompetent children, but extremely rarely with only generalized edema. Clinical Presentation and Intervention: A previously healthy 5-year-old boy presented with generalized edema without any other symptoms. He had hypoalbuminemia but no proteinuria. He was evaluated for gastrointestinal protein loss, and hypertrophic gastropathy was revealed on esophagogastroduodenoscopy. Meanwhile, CMV infection was detected by serologic tests and polymerase chain reaction in the blood. He recovered spontaneously within a week. Conclusion: CMV-related protein-losing gastropathy may present with generalized edema without any gastrointestinal symptoms.
ISSN:1011-7571
1423-0151
DOI:10.1159/000500511