Abstract 9361: Role of 3 D Speckle Tracking Echocardiography to Detect Left Ventricular Dysfunction. Initial Experience in a Routine Clinical Laboratory

• Published in: Circulation (New York, N.Y.) N.Y.), 2011-11, Vol.124 (suppl_21)
• Main Authors: Saha, Samir, Kiotsekoglou, Anatoli, Toole, Rena, Gopal, Aasha S
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.124.suppl_21.A9361

Abstract only Background: Left ventricular (LV) volumes and strain obtained by 3D speckle tracking echocardiography requires investigation to assess the relative discriminatory power of one over the other that has not been studied in a clinical laboratory, thereby justifying the rationale of this study. Methods: 38 human subjects with normal echocardiogram and 88 subjects (58 ±14 years, 53 M) with abnormal echocardiogram (structural and/or coronary artery disease) underwent 3 D speckle tracking echocardiography (3D-STE) using a custom SW (Tomtec). The data obtained were end- systolic and diastolic volumes (ESV, EDV), LVEF, 3D strain, 3D circumferential strain (CS %) and 3D radial strain (RS %). Objective of the study was to assess the comparative diagnostic power of the 3D STE data to identify diseased LV. Results: ROC analyses yielded areas under the curve (AUC) values for ESV (0.85), LVEF (0.84),3D strain ( 0.81), 3D RS%( 0.79), 3D CS%( 0.76), and EDV ( 0.76). Pairwise comparison of the AUC showed that ESV had a significantly greater AUC than EDV (p