Abstract 13480: Utility of Combined Assessment of Exercise Oscillatory Breathing and Global Circumferential Strain to Predict Cardiac Events in Heart Failure Patients

• Published in: Circulation (New York, N.Y.) N.Y.), 2014-11, Vol.130 (suppl_2)
• Main Authors: Tanaka, Hidekazu, Tsuboi, Yasunori, Matsumoto, Kensuke, Dokuni, Kuniko, Hatani, Yutaka, Matsuzoe, Hiroki, Hatazawa, Keiko, Toki, Hiromi, Shimoura, HIroyuki, Ooka, Junichi, Sano, Hiroyuki, Sawa, Takuma, Motoji, Yoshiki, Mochizuki, Yasuhide, Tatsumi, Kazuhiro, Sakai, Yoshitada, Hirata, Ken-ichi
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.130.suppl_2.13480

Abstract only Background: The occurrence of cardiopulmonary exercise testing-derived exercise oscillatory breathing (EOB) is a predictor of survival in heart failure (HF) patients. Whereas, it was recently reported that global circumferential strain (GCS) as assessed by two-dimensional speckle-tracking imaging reflects intrinsic left ventricular (LV) myocardial function and is a powerful predictor of cardiovascular events, and thus appears to be a better predictive parameter than global LV function, including LV ejection fraction (EF). The objectives of our study were to test the hypothesis that a combined assessment of EOB and GCS can further enhance the ability of the method to predict cardiac events in HF patients. Methods: A total of 86 HF patients with LVEF of 44±11% underwent cardiopulmonary exercise testing and echocardiography. GCS was determined as the peak global speckle-tracking strain from mid-LV short-axis view, and GCS of