Abstract 10447: The Relationship Between Cerebral Regional Oxygen Saturation During Extracorporeal Cardiopulmonary Resuscitation and Neurological Outcome

• Published in: Circulation (New York, N.Y.) N.Y.), 2015-11, Vol.132 (Suppl_3 Suppl 3), p.A10447-A10447
• Main Authors: Hirose, Tomoya, Ehara, Naoki, Shiozaki, Tadahiko, Wakai, Akinori, Nishimura, Tetsuro, Mori, Nobuto, Ohnishi, Mitsuo, Sadamitsu, Daikai, Shimazu, Takeshi
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.132.suppl_3.10447

IntroductionIn recent years, measurement of cerebral regional oxygen saturation (rSO2) has attracted attention during resuscitation. The objective of this study was to clarify the relationship between serial changes in cerebral rSO2 during extracorporeal cardiopulmonary resuscitation (ECPR) and neurological outcome. HypothesisCerebral rSO2 during ECPR would predict neurological outcome.MethodsWe measured serial changes in cerebral rSO2 in patients with out-of-hospital cardiac arrest before and after ECPR in Osaka National Hospital.ResultsFrom January 2013 through March 2015, serial changes in cerebral rSO2 were evaluated in 16 patients. Their outcomes as measured by the Glasgow Outcome Scale (GOS) score at discharge included Good Recovery (GR) in 4 patients, Vegetative State (VS) in 2 patients, and Death (D) in 10 patients. In the poor neurological group (VS and Dn=12, 52.8±4.0 years), the values of cerebral rSO2 increased significantly with ECPR (5 min before ECPR52.0±1.8%; 2 min before56.1±2.3%; 2 min after ECPR63.5±2.2%; 5 min after66.4±2.2%; 10 min after67.6±2.3% [p