Abstract 10902: Association Between Funding Sources and the Scope and Outcomes of Cardiovascular Clinical Trials: A Systematic Review

IntroductionLimited data are available exploring trends and influence of funding sources on cardiovascular clinical trials scope and outcomes.MethodsWe abstracted data from all phase II to IV cardiovascular clinical trials from 2001 to 2012 published in the 8 highest Web of Science impact factor jou...

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Published in:Circulation (New York, N.Y.) N.Y.), 2015-11, Vol.132 (Suppl_3 Suppl 3), p.A10902-A10902
Main Authors: Vaduganathan, Muthiah, Samman-Tahhan, Ayman, Papadimitriou, Lampros, Georgiopoulou, Vasiliki V, Greene, Stephen J, Kalogeropoulos, Andreas P, Peterson, Eric, Fonarow, Gregg C, Gheorghiade, Mihai, Butler, Javed
Format: Article
Language:English
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Summary:IntroductionLimited data are available exploring trends and influence of funding sources on cardiovascular clinical trials scope and outcomes.MethodsWe abstracted data from all phase II to IV cardiovascular clinical trials from 2001 to 2012 published in the 8 highest Web of Science impact factor journals using both a PubMed database and manual journal search.ResultsOf the 1,224 trials evaluated, 581 (47.5%) were funded by industry, 273 (22.3%) by universities or other non-profit organizations, 159 (13%) by governments, 127 (10.4%) were jointly funded, and 84 (6.9%) did not report funding source. Proportion of industry and government funded trials trended down, while the proportion of non-profit and jointly-funded trials increased over time (P
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.132.suppl_3.10902