Abstract 13093: Predictors for the Favorable Change of Fibrous-cap in Non-culprit Lipid Plaques in Response to Statin Therapy: A Serial Optical Coherence Tomography Study

IntroductionPrevious studies demonstrated that statins improved fibrous cap thickness (FCT) in patients with coronary artery disease. However, factors affecting the favorable FCT change in response to statin therapy remain unknown.AimTo identify the clinical factors for favorable FCT change of non-c...

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Published in:Circulation (New York, N.Y.) N.Y.), 2015-11, Vol.132 (Suppl_3 Suppl 3), p.A13093-A13093
Main Authors: Minami, Yoshiyasu, Ong, Daniel S, Uemura, Shiro, Wang, Zhao, Aguirre, Aaron D, Mukhopadhyay, Shankha, Soeda, Tsunenari, Vergallo, Rocco, Gao, Lei, Xing, Lei, Lee, Hang, Yu, Bo, Jang, Ik-Kyung
Format: Article
Language:English
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Summary:IntroductionPrevious studies demonstrated that statins improved fibrous cap thickness (FCT) in patients with coronary artery disease. However, factors affecting the favorable FCT change in response to statin therapy remain unknown.AimTo identify the clinical factors for favorable FCT change of non-culprit coronary plaques with statin therapy in patients with coronary artery disease.MethodsA total of 152 non-culprit plaques from 90 patients who were treated with statin and had serial optical coherence tomography (OCT) imaging at baseline and follow-up were included. FCT was assessed at the thinnest portion within the entire plaque.ResultsThe mean FCT was improved from 105.7 ± 52.3 μm to 128.4 ± 60.7 μm (P
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.132.suppl_3.13093