Abstract 16326: Safety and Efficacy of Novel Oral Anticoagulants in Subjects With Atrial Fibrillation in Relation to Renal Function: Meta-analysis of Randomized Clinical Trials

IntroductionThe efficacy and safety of novel oral anticoagulants (NOACs) has not been assessed in subjects with renal impairment.MethodsWe performed a meta-analysis of RCTs comparing NOACs with warfarin in patients with atrial fibrillation (AF), in relation to renal function estimated by glomerular...

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Published in:Circulation (New York, N.Y.) N.Y.), 2015-11, Vol.132 (Suppl_3 Suppl 3), p.A16326-A16326
Main Authors: Del Carpio, Freddy, Gharacholou, Shahyar M, Branson, Andrea M, Paletta, Dawn M, Brose, Pamela K, Asirvatham, Samuel J
Format: Article
Language:English
Online Access:Get full text
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Summary:IntroductionThe efficacy and safety of novel oral anticoagulants (NOACs) has not been assessed in subjects with renal impairment.MethodsWe performed a meta-analysis of RCTs comparing NOACs with warfarin in patients with atrial fibrillation (AF), in relation to renal function estimated by glomerular filtration rate (GFR)normal (GFR>80 ml/min/1.73m2), mild (50-80 mL/min/1.73m2), and moderate (
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.132.suppl_3.16326