Abstract 10417: Parity and Progression of Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis

IntroductionCoronary artery calcium (CAC) is a measure of subclinical atherosclerosis and predicts cardiovascular disease (CVD) events. Higher parity, the number of live births, has been shown to relate to CVD. We examined whether parity is associated with progression of CAC as one pathway to CVD. M...

Full description

Saved in:
Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2021-11, Vol.144 (Suppl_1), p.A10417-A10417
Main Authors: Vu, Kimberly, Michos, Erin, FAN, WENJUN, Evans, Jonathan, Mongraw-chaffin, Morgana, Budoff, Matthew, Wong, Nathan D
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:IntroductionCoronary artery calcium (CAC) is a measure of subclinical atherosclerosis and predicts cardiovascular disease (CVD) events. Higher parity, the number of live births, has been shown to relate to CVD. We examined whether parity is associated with progression of CAC as one pathway to CVD. MethodsWe studied 2772 women aged 44 to 84 years free of CVD at baseline in the prospective Multi-Ethnic Study of Atherosclerosis. Parity was examined continuously as number of live births as well as by categories0-1 (reference), 2-3, and ≥4 in relation to change in CAC score from baseline to follow-up from repeat exams up to 11 years later. We used linear mixed effect models to account for repeated measures when assessing whether progression of CAC was associated with parity, adjusted for baseline CAC and other risk factors. ResultsWomen with higher parity had greater annualized progression of CAC scores (unadjusted p
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.144.suppl_1.10417