Abstract 10734: Assessment of Cardiovascular Disease and Mortality Among Black Patients with Gout

• Published in: Circulation (New York, N.Y.) N.Y.), 2021-11, Vol.144 (Suppl_1), p.A10734-A10734
• Main Authors: chandrakumar, Harshith P, Puskoor, Anoop V, Chillumuntala, Seeta, Sharif, Sara, Cepeda Mora, Diego, Gupta, Tanuj, Tadayoni, Ashkan, Celiker, Pelin, Yakoubovitch, Stephanie, Tsai, Andrew, Chiu, Courtney, Kazi, Anan, Frielich, Michael, Saleh, Ahmad, Moon, Seung Jae, Cruickshank, Kingsley, Katz, Julie, Salciccioli, Louis, McFarlane, isabel M
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.144.suppl_1.10734

IntroductionWhile the association between gout and cardiovascular disease (CVD) has been extensively studied, scarce data is available for the Black population. We aimed to assess, in a predominantly Black urban population with gout, the prevalence of traditional CVD risk factors, CV outcomes, and the strength of the association between gout and CVD after adjusting for CVD risk factors. HypothesisBlack patients with gout have higher CVD rates compared to a matched cohort without gout. MethodsCross-sectional analysis of data obtained from the EMR of gout patients followed at our primary care clinics. Patients were identified by ICD codes and compared to age, sex and race matched non- gout cohort. Descriptive data was obtained, and logistic regression used to assess the strength of association between gout and CVD, before and after adjustment for CVD risk factors including obesity, DM, HTN, dyslipidemia and smoking. ResultsThere were 471 patients with gout with a mean age of 63.7 ± 0.5 years (mean ±SEM); 89% were Black, 63% were men, mean BMI was 31.3 ± 0.4 Kg/m2. HTN, DM and dyslipidemia were present in 89%, 46% and 52% respectively.Compared to controls, patients with gout had significantly higher rates of angina, arrythmia, CAD/stents, MI, CABG, CVA, and PVD. The odds ratio (OR) for CVD = 4.5 (3.3-6.2) (95% CI), p