Abstract 10490: Sex Disparities in Cardiovascular Research Are Influenced by Senior Investigator Gender

• Published in: Circulation (New York, N.Y.) N.Y.), 2022-11, Vol.146 (Suppl_1), p.A10490-A10490
• Main Authors: Veizades, Stefan, Auer, Natasha, Sandifer, Jaylen, Mueller, Adrienne, Vera, Carlos D, Nguyen, Patricia K
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.146.suppl_1.10490

IntroductionThe clinical presentation and management of cardiovascular diseases has been shown to be sex-specific, yet, historically, cardiovascular research participants have been predominantly male. One cause for this discrepancy could be gender-based bias on the part of studies' senior investigators. MethodsWe screened 749 randomly selected clinical research articles from 8 top cardiovascular research journals, published between 2015 and 2020. We predicted the gender of senior investigators by using the genderize.io gender-coding algorithm. We then used t-tests to determine the relationship between putative senior author gender and number of study participants of each sex. ResultsCardiovascular research cohorts were 39.74% female. Compared to studies senior-authored by men, cohorts of female senior-authored studies included 11.36% more female participants (p0.05=ns, p≤0.05=*, p≤0.01=**, p≤0.001=***, p≤0.0001=***.