Abstract 10931: Impact of Atrial Fibrillation Type (paroxysmal vs. Non-paroxysmal) on Long-Term Clinical Outcomes: The Raffine Registry Subanalysis

• Published in: Circulation (New York, N.Y.) N.Y.), 2022-11, Vol.146 (Suppl_1), p.A10931-A10931
• Main Authors: Wada, Hideki, MIYAUCHI, Katsumi, SUWA, Satoru, Miyazaki, Sakiko, Hayashi, Hidenori, MIYAZAKI, Tadashi, Sumiyoshi, Masataka, NAKAZATO, YUJI, Minamino, Tohru, Daida, Hiroyuki
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.146.suppl_1.10931

BackgroundType of atrial fibrillation (AF) (paroxysmal or non-paroxysmal) is important for determining the therapeutic management. However, prognostic impact of AF type on incidence of cardiovascular events remains uncertain. MethodsWe investigated patients with AF who were selected from an observational, multicenter, prospective registry (RAFFINE) comprising 4 university hospitals and 50 general hospital / clinics in Japan between 2013 and 2015. In this subanalysis of the RAFFINE trial, patients were divided into 2 groups according to their AF pattern at the time of enrollment. The primary outcome was composite of all-cause death, ischemic stroke, and heart failure related hospitalization. ResultsAmong 3,845 patients, 1,472 (38.3%) and 2,373 (61.7%) were paroxysmal and non-paroxysmal AF, respectively. Patients with non-paroxysmal AF were older, higher CHADS2 score and had higher prevalence of comorbidities compared with those with paroxysmal AF. During a median follow-up of 3.7 years, 681 (17.7%) primary endpoints were identified. Cumulative incidences of primary endpoint were significantly higher in non-paroxysmal AF group (log-rank p