Abstract 11288: Conduction Velocity is Slower in Corridors Traversing Lipomatous Metaplasia Than in Corridors Traversing Scar in Chronic Infarcts

IntroductionWe sought to examine the association of infarct scar versus lipomatous metaplasia (LM) with impulse conduction velocity (CV) in putative ventricular tachycardia (VT) corridors that traverse the infarct zone in patients with prior myocardial infarction (MI). MethodsThe cohort included 31...

Full description

Saved in:
Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2022-11, Vol.146 (Suppl_1), p.A11288-A11288
Main Authors: Xu, Lingyu, Zahid, Sohail, Pourmousavi Khoshknab, MirMilad, Moss, Juwann, Berger, Ronald D, Chrispin, Jonathan, Callans, David J, Marchlinski, Francis E, Zimmerman, Stefan, Han, Yuchi, Desjardins, Benoit, Trayanova, Natalia, Nazarian, Saman
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:IntroductionWe sought to examine the association of infarct scar versus lipomatous metaplasia (LM) with impulse conduction velocity (CV) in putative ventricular tachycardia (VT) corridors that traverse the infarct zone in patients with prior myocardial infarction (MI). MethodsThe cohort included 31 patients from the prospective Intra-Myocardial Fat Deposition and Ventricular Tachycardia in Ischemic Cardiomyopathy (INFINITY) study. CV was calculated as the mean CV between that point and five adjacent points along the activation wavefront using an automated Python script in myocardial scar, border zone (BZ), and potential viable corridors defined by late gadolinium enhancement (LGE)-cardiac magnetic resonance (CMR), and LM identified by computed tomography (CT). Both image sets were registered with electroanatomic maps (EAM). ResultsRegions with LM exhibited lower myocardial CV than scar (median 12.0 vs. 13.5 cm/s, P
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.146.suppl_1.11288