Abstract 15314: Rhythm Outcome of Persistent Atrial Fibrillation Ablation Depending on the Timing of the First Electrocardiographic Documentation

Abstract only Introduction: Recently, delaying atrial fibrillation (AF) catheter ablation (AFCA) by 12 months for antiarrhythmic drug (AAD) management didn't result in reduced ablation efficacy. In this study, we explored AFCA rhythm outcomes based on the diagnosis-to-ablation time (DAT) in AAD...

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Published in:Circulation (New York, N.Y.) N.Y.), 2023-11, Vol.148 (Suppl_1)
Main Authors: Kim, Hongju, Kim, Kipoong, Kim, Daehoon, Choi, Sung Hwa, Kim, Moon-Hyun, Park, Je W, Yu, Hee Tae, Uhm, Jae-Sun, JOUNG, BOYOUNG, LEE, Moon Hyoung, Pak, Hui-Nam
Format: Article
Language:English
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Summary:Abstract only Introduction: Recently, delaying atrial fibrillation (AF) catheter ablation (AFCA) by 12 months for antiarrhythmic drug (AAD) management didn't result in reduced ablation efficacy. In this study, we explored AFCA rhythm outcomes based on the diagnosis-to-ablation time (DAT) in AAD-resistant persistent AF (PeAF). Methods: We included 1,038 AAD-resistant PeAF patients with clear DAT (male 79.8%, 61.0 [54.0-68.0]) who underwent AFCA followed by guidelines-based regular rhythm follow-up. Before AFCA, all patients underwent optimal medial therapy (AAD) with or without cardioversion. Patients on AADs, who experienced paroxysmal type recurrence, were classified as AAD-partial-responders, while those maintaining PeAF were categorized as AAD-non-responders. We determined the DAT cut-off for rhythm outcome using a maximum likelihood approach in a Cox regression model. Results: AAD-partial-responders showed higher body mass index (p=0.007), larger left atrial diameter (p
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.148.suppl_1.15314