Abstract 19078: Coronary Artery Disease in Very Young Adults: Characteristics, Associated Factors and In-Hospital Mortality

• Published in: Circulation (New York, N.Y.) N.Y.), 2023-11, Vol.148 (Suppl_1)
• Main Authors: Ndunda, Paul M, pachariyanon, pavida, Golden, Joseph, Nwagbara, Kenechukwu, Pierotti, Tyler, Dacdac, Kyle Felipe, Modi, Morni, Hawkins, Alison, Lobello, Alyssa, Modi, Kalgi
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.148.suppl_1.19078

Abstract only Introduction: Premature CAD carries a poor long-term prognosis. However, there is little data on CAD in very young adults. Understanding the characteristics and associated factors in this population is paramount to the prevention and improvement of outcomes of CAD. Aims To assess characteristics, associated factors, and in-hospital mortality in adults aged 18-35 years with significant CAD (S-CAD) undergoing invasive coronary angiography. Methods: This is a retrospective cohort study of patients who underwent coronary angiography in a single academic center from 2003-2023. S-CAD was defined as major epicardial CAD with at least 50% stenosis. Chi-square, Fischer exact, and Mann Whitney U tests were used to analyze categorical and continuous variables respectively. Logistic regression was used for multivariable analysis. Results: A total of 330 patients were included in the study. Patient characteristics are presented in table 1. Factors associated with the incidence of S-CAD include ST elevation, elevated troponin, total cholesterol, LDL, triglyceride, glucose, high WBC & platelet count, low Platelet: WBC ratio, and no cocaine use (p