A pooled analysis of individual patient data from trials of endarterectomy for symptomatic carotid stenosis: efficacy of surgery in important subgroups

65 Benefit from carotid endarterectomy (CEA) depends on the degree of symptomatic stenosis, but is also likely to be influenced by other clinical and angiographic characteristics. However, individual trials have been too small to allow reliable subgroup analysis. We therefore studied pooled individu...

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Bibliographic Details
Published in:Stroke (1970) 2001-01, Vol.32 (suppl_1), p.328-328
Main Authors: Dr, Peter M Rothwell, Dr, Sergei A Gutnikov, Professor, Marc R Mayberg, Professor, Charles P Warlow, Professor, Henry Jm Barnett
Format: Article
Language:English
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Summary:65 Benefit from carotid endarterectomy (CEA) depends on the degree of symptomatic stenosis, but is also likely to be influenced by other clinical and angiographic characteristics. However, individual trials have been too small to allow reliable subgroup analysis. We therefore studied pooled individual patient data from the European Carotid Surgery Trial, the North American Symptomatic Carotid Endarterectomy Trial and the Veterans Administration trial #309. We determined the effect of CEA in 11 predefined subgroups: age (
ISSN:0039-2499
1524-4628
DOI:10.1161/str.32.suppl_1.328